Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], vol.188, no.3, pp.248-54, 2012 (Journal Indexed in SCI Expanded)
Article / Article
Title of Journal :
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]
Survivin protein, human, Aurora B kinase, Squamous cell carcinoma of the head and neck, Radiotherapy, Biomarkers, MITOTIC KINASE, MOLECULAR-MECHANISM, APOPTOSIS, CARCINOMA, PROGNOSIS, INHIBITORS, THERAPY, INCENP, GENE
Background and purpose. Survivin is one of the apoptosis inhibitor proteins. Together with Aurora B, it also plays a role in regulating several aspects of mitosis. High expression of these markers is correlated with malignant behavior of various cancers and resistance to therapy. Our aim was to evaluate the prognostic role of these markers in head and neck cancers.