The role of insulin - like growth factor-1 on steatohepatitis

Dal K., Bulur O., Ata N., Yeniova A. O., Baser S., Karakaya S., ...Daha Fazla

ACTA GASTRO-ENTEROLOGICA BELGICA, cilt.80, sa.1, ss.21-24, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 80 Sayı: 1
  • Basım Tarihi: 2017
  • Dergi Adı: ACTA GASTRO-ENTEROLOGICA BELGICA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.21-24
  • Anahtar Kelimeler: IGF-1, non-alcoholic fatty liver disease, FATTY LIVER-DISEASE, GH REPLACEMENT THERAPY, HORMONE, DEFICIENCY, DYSFUNCTION, DELETION, PROTEIN, IGF
  • Gazi Üniversitesi Adresli: Hayır

Özet

Purpose : Recent studies have revealed that growth hormone and STAT5 were related to hepatosteatosis in mice. Loss of signal transducer and activator of transcription factor-5 leads to hepatosteatosis and impaired liver regeneration. We aimed to investigate the role of IGF-1 in steatosis with normal (SNLFT) and disturbed liver function tests (SDLFT) in humans.