The role of insulin - like growth factor-1 on steatohepatitis


Dal K., Bulur O., Ata N., Yeniova A. O. , Baser S., Karakaya S., ...More

ACTA GASTRO-ENTEROLOGICA BELGICA, vol.80, no.1, pp.21-24, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 80 Issue: 1
  • Publication Date: 2017
  • Journal Name: ACTA GASTRO-ENTEROLOGICA BELGICA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.21-24
  • Keywords: IGF-1, non-alcoholic fatty liver disease, FATTY LIVER-DISEASE, GH REPLACEMENT THERAPY, HORMONE, DEFICIENCY, DYSFUNCTION, DELETION, PROTEIN, IGF
  • Gazi University Affiliated: Yes

Abstract

Purpose : Recent studies have revealed that growth hormone and STAT5 were related to hepatosteatosis in mice. Loss of signal transducer and activator of transcription factor-5 leads to hepatosteatosis and impaired liver regeneration. We aimed to investigate the role of IGF-1 in steatosis with normal (SNLFT) and disturbed liver function tests (SDLFT) in humans.