The role of insulin - like growth factor-1 on steatohepatitis

Dal, Kursat; Bulur, Oktay; Ata, Naim; Yeniova, Abdullah; Baser, Salih; Karakaya, Serdar; Unsal, OKTAY; Dagdeviren, Murat; Karadag, Ibrahim; Beyan, Esin; Ertugrul, Derun

The role of insulin - like growth factor-1 on steatohepatitis

Dal K., Bulur O., Ata N., Yeniova A. O., Baser S., Karakaya S., ...Daha Fazla

ACTA GASTRO-ENTEROLOGICA BELGICA, cilt.80, sa.1, ss.21-24, 2017 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 80 Sayı: 1
Basım Tarihi: 2017
Dergi Adı: ACTA GASTRO-ENTEROLOGICA BELGICA
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.21-24
Anahtar Kelimeler: IGF-1, non-alcoholic fatty liver disease, FATTY LIVER-DISEASE, GH REPLACEMENT THERAPY, HORMONE, DEFICIENCY, DYSFUNCTION, DELETION, PROTEIN, IGF
Gazi Üniversitesi Adresli: Hayır

Özet

Purpose : Recent studies have revealed that growth hormone and STAT5 were related to hepatosteatosis in mice. Loss of signal transducer and activator of transcription factor-5 leads to hepatosteatosis and impaired liver regeneration. We aimed to investigate the role of IGF-1 in steatosis with normal (SNLFT) and disturbed liver function tests (SDLFT) in humans.