ANNALS OF THORACIC SURGERY, vol.79, no.2, pp.666-671, 2005 (SCI-Expanded)
Background. Cognitive dysfunction (as an indicator of cerebral dysfunction after open heart surgery) was observed in as many as 70% of patients who underwent cardiopulmonary bypass. S-100beta; protein is a sensitive indicator of cerebral injury. We aimed to compare the effects of hydroxyethyl starch and Ringer lactate prime solutions in the protection of cerebral tissue in cardiopulmonary bypass using serum S-100beta protein levels and informative cognitive tests.