Risk of Psychotropic Drug Interactions in Real World Settings: a Pilot Study in Patients with Schizophrenia and Schizoaffective Disorder

Sengul M. C. B., Karadag F., Sengul C., Karakulah K., Kalkanci O., Herken H.

KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY, cilt.24, sa.3, ss.235-247, 2014 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 24 Sayı: 3
  • Basım Tarihi: 2014
  • Doi Numarası: 10.5455/bcp.20140311041445
  • Dergi Adı: KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.235-247
  • Anahtar Kelimeler: schizophrenia, schizoaffective disorder, psychotropic, polypharmacy, drug interaction, TORSADE-DE-POINTES, ANTIPSYCHOTIC POLYPHARMACY, QTC PROLONGATION, BIPOLAR DISORDER, PLASMA-LEVEL, LITHIUM, PRESCRIPTION, PREVALENCE, INPATIENTS, RISPERIDONE
  • Gazi Üniversitesi Adresli: Evet

Özet

Objective: The rate of polypharmacy is increasing in patients with psychotic disorders. Polypharmacy is defined as the concomitant use of two or more drugs at a time. As most psychotropic medications are metabolized via the cytochrome enzyme system, it is easy to predict that polypharmacy will increase the risk of drug-drug interactions. This study was planned to evaluate the interaction risks of medications used by patients with a diagnosis of schizophrenia and schizoaffective disorder.