Atıf İçin Kopyala
Ceneli O., Aki S. Z., Kucuk B. C., Tokcaer A. B., Kuruoglu R., Yagci M.
TURKISH JOURNAL OF HEMATOLOGY, cilt.27, sa.4, ss.250-256, 2010 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
27
Sayı:
4
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Basım Tarihi:
2010
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Doi Numarası:
10.5152/tjh.2010.46
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Dergi Adı:
TURKISH JOURNAL OF HEMATOLOGY
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
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Sayfa Sayıları:
ss.250-256
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Anahtar Kelimeler:
Cobalamin deficiency, autonomic dysfunction, dysautonomia, autonomic neuropathy, serum cytokine levels, EPIDERMAL-GROWTH-FACTOR, HEART-RATE-VARIABILITY, NECROSIS-FACTOR-ALPHA, VITAMIN-B-12 DEFICIENCY, CEREBROSPINAL-FLUID, SPINAL-CORD, ABNORMALITIES, RATS
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Gazi Üniversitesi Adresli:
Evet
Özet
Objective: The imbalance between neurotoxic cytokine tumor necrosis factor-alpha (TNF-alpha) and neurotrophic cytokines epidermal growth factor (EGF) and interleukin-6 (IL-6) plays a role in the pathogenesis of cobalamin (Cbl) deficiency-induced neuropathy. The aim of this study was to evaluate autonomic nervous system dysfunction and to look for any relationship between autonomic nervous system disturbances and serum cytokine levels (TNF-alpha, EGF, IL-6) in patients with Cbl deficiency.