Role of leptin in growth and adiposity in early infancy: Impact of nutritional pattern

Duyan A. C. , Sahin F., Camurdan M. O. , Bideci A., Cinaz P.

INDIAN PEDIATRICS, vol.44, no.9, pp.687-690, 2007 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 44 Issue: 9
  • Publication Date: 2007
  • Title of Journal : INDIAN PEDIATRICS
  • Page Numbers: pp.687-690


This study was planned to investigate leptin levels under different models of nutrition and their relation with anthropometric parameters in early infancy. Sixty four infants (28 exclusively breast-fed, 15 exclusively formula-fed and 21 mixed-fed), aged 4 months were included and their leptin, insulin-like growth factor-I (IGF-1), and IGF binding protein-3 (IGFBP-3) levels were measured. Leptin, IGF-1 and IGFBP-3 levels of the three groups here not statistically different (P>0.05). The results of our study questions the role of leptin as a link between nutritional pattern and adiposity-growth in early infancy.