Use of Amplitude-integrated Electroencephalography in Neonates with Special Emphasis on Hypoxic-ischemic Encephalopathy and Therapeutic Hypothermia


GÜCÜYENER K.

JOURNAL OF CLINICAL NEONATOLOGY, vol.5, no.1, pp.18-30, 2016 (Journal Indexed in ESCI) identifier

  • Publication Type: Article / Review
  • Volume: 5 Issue: 1
  • Publication Date: 2016
  • Doi Number: 10.4103/2249-4847.173272
  • Title of Journal : JOURNAL OF CLINICAL NEONATOLOGY
  • Page Numbers: pp.18-30

Abstract

Recognizing the need for neurological monitoring in critically ill neonates such as the other vital parameters, neonatologists, and neurologists is becoming more familiar and comfortable with the use of amplitude-integrated electroencephalography (aEEG) in the neonatal intensive care unit, with minimal training and can be interpreted by care providers without neurophysiology backgrounds. In its simplest form, aEEG is a processed single-channel electroencephalogram that is iltered and time compressed. Current evidence demonstrates that aEEG is useful to monitor cerebral background activity, diagnose and treat seizures, and predict neurodevelopmental outcomes for preterm and term infants. This review aims to explain the fundamentals behind aEEG and its clinical applications specially referring to neonatal hypoxic-ischemic encephalopathy and hypothermia.