Spontaneous resolution of hemophagocytic syndrome and disseminated intravascular coagulation associated with parvovirus B19 infection in a previously healthy child


Kaya Z., Ozturk G., Gursel T., Bozdayi G.

JAPANESE JOURNAL OF INFECTIOUS DISEASES, vol.58, no.3, pp.149-151, 2005 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 58 Issue: 3
  • Publication Date: 2005
  • Title of Journal : JAPANESE JOURNAL OF INFECTIOUS DISEASES
  • Page Numbers: pp.149-151

Abstract

A 10-year-old male with a brain abscess developed pancytopenia, liver dysfunction, disseminated intravascular coagulation (DIC) and decrease of immunoglobulin A (IgA) level during postoperative antibiotic and anticonvulsant therapy. A bone marrow examination revealed hemophagocytosis. Real-time PCR revealed parvovirus B 19 infection. The hemophagocytic syndrome resolved without specific treatment. To our knowledge, this is the first report of a spontaneous resolution of parvovirus B19-associated hemophagocytic syndrome and DIC.