Spontaneous resolution of hemophagocytic syndrome and disseminated intravascular coagulation associated with parvovirus B19 infection in a previously healthy child


Kaya Z., Ozturk G., Gursel T., Bozdayi G.

JAPANESE JOURNAL OF INFECTIOUS DISEASES, cilt.58, ss.149-151, 2005 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 58 Konu: 3
  • Basım Tarihi: 2005
  • Dergi Adı: JAPANESE JOURNAL OF INFECTIOUS DISEASES
  • Sayfa Sayıları: ss.149-151

Özet

A 10-year-old male with a brain abscess developed pancytopenia, liver dysfunction, disseminated intravascular coagulation (DIC) and decrease of immunoglobulin A (IgA) level during postoperative antibiotic and anticonvulsant therapy. A bone marrow examination revealed hemophagocytosis. Real-time PCR revealed parvovirus B 19 infection. The hemophagocytic syndrome resolved without specific treatment. To our knowledge, this is the first report of a spontaneous resolution of parvovirus B19-associated hemophagocytic syndrome and DIC.