The in vivo anthelmintic efficacy of some Verbascum species growing in Turkey

KOZAN E., ÇANKAYA İ. İ., KAHRAMAN Ç., AKKOL E., Akdemir Z.

EXPERIMENTAL PARASITOLOGY, cilt.129, sa.2, ss.211-214, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 129 Sayı: 2
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1016/j.exppara.2011.06.005
  • Dergi Adı: EXPERIMENTAL PARASITOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.211-214
  • Anahtar Kelimeler: Anthelmintic activity, Aspiculuris tetraptera, Verbascum, Scrophulariaceae, SYPHACIA-OBVELATA, MEDICINAL-PLANTS, MICE, METABOLITES, IVERMECTIN
  • Gazi Üniversitesi Adresli: Evet

Özet

Verbascum L (Scrophulariaceae) species are used for desiccating wounds and as a fish poison in Anatolia as well as for diarrhea and dysentery of animals in several countries. To further evaluate their activity, methanolic extracts obtained from 13 Verbascum species growing in Turkey, including V. chionophyllum Hub.-Mor., V. cilicicum Boiss., V. dudleyanum (Hub.-Mor.) Hub.-Mor., V. lasianthum Boiss., V. latisepalum Hub.-Mor., V: mucronatum Lam., V. olympicum Boiss., V. pterocalycinum var. mutense Hub.-Mor., V. pycnostachyum Boiss. & Heldr., V. salviifolium Boiss.. V. splendidum Boiss., V. stachydifolium Boiss. & Heldr. and V. uschackense (Murb.) Hub.-Mor. were evaluated for their in vivo anthelmintic activity. The extracts from V. lasianthum, V. latisepalum, V. mucronatum and V. salviifolum showed the highest inhibitory rates against Aspiculuris tetraptera at 100 mg/kg in mice. Additionally, extracts from V. dudleyanum and V. pterocalycinum var. mutense were found generally highly effective. The remaining species did not show any activity. Results of the present study support the utilization of these plant species employed in Turkish folk medicine. (C) 2011 Elsevier Inc. All rights reserved.