Plasma neutrophil gelatinase-associated lipocalin levels in acute myocardial infarction and stable coronary artery disease

ŞAHİNARSLAN A., Kocaman S. A., Bas D., Akyel A., Ercin U., Zengin O., ...Daha Fazla

CORONARY ARTERY DISEASE, cilt.22, sa.5, ss.333-338, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22 Sayı: 5
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1097/mca.0b013e3283472a71
  • Dergi Adı: CORONARY ARTERY DISEASE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.333-338
  • Anahtar Kelimeler: biomarkers, inflammation, ischemic heart disease, myocardial infarction, plaque instability, C-REACTIVE PROTEIN, CONTRAST NEPHROPATHY, LEUKOCYTE ACTIVATION, HEART-DISEASE, SEVERITY, NGAL, MATRIX-METALLOPROTEINASE-9, ATHEROSCLEROSIS, INTERVENTIONS, PLAQUES
  • Gazi Üniversitesi Adresli: Evet

Özet

Introduction Inflammation and polymorphonuclear neutrophils are shown to be important in the pathogenesis of acute myocardial infarction (AMI). Neutrophil gelatinase-associated lipocalin (NGAL) is secreted from neutrophils and may increase the proteolytic activity within the atherosclerotic plaque. We aimed to investigate whether the plasma levels of NGAL are higher in patients with AMI compared with stable coronary artery disease (CAD).