Management of children with congenital nephrotic syndrome: challenging treatment paradigms

Dufek S., Holtta T., Trautmann A., Ylinen E., ALPAY H., Ariceta G., ...Daha Fazla

NEPHROLOGY DIALYSIS TRANSPLANTATION, cilt.34, sa.8, ss.1369-1377, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 34 Sayı: 8
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1093/ndt/gfy165
  • Dergi Adı: NEPHROLOGY DIALYSIS TRANSPLANTATION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1369-1377
  • Anahtar Kelimeler: bilateral nephrectomies, congenital nephrotic syndrome, genotype-phenotype correlation, management approach, NPHS1, DIFFUSE MESANGIAL SCLEROSIS, STEROID-RESISTANT, GENOTYPE/PHENOTYPE CORRELATIONS, GLOMERULAR PROTEIN, 1ST YEAR, MUTATIONS, NPHS1, NEPHRIN, SURVIVAL, LIFE
  • Gazi Üniversitesi Adresli: Evet

Özet

Background. Management of children with congenital nephrotic syndrome (CNS) is challenging. Bilateral nephrectomies followed by dialysis and transplantation are practiced in most centres, but conservative treatment may also be effective.