Distribution of secreted aspartyl proteinases using a polymerase chain reaction assay with SAP specific primers in Candida albicans isolates
FOLIA MICROBIOLOGICA, cilt.50, sa.5, ss.409-413, 2005 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 50 Sayı: 5
- Basım Tarihi: 2005
- Doi Numarası: 10.1007/bf02931422
- Dergi Adı: FOLIA MICROBIOLOGICA
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.409-413
- Gazi Üniversitesi Adresli: Evet
Özet
Secreted aspartyl proteinase (Sap) distribution among different C. albicans isolates was determined using SAP-specific primers in polymerase chain reaction (PCR) assay. SAP1, SAP2, and SAP3 were detected in 13 of 40 (32.5 %), SAP4 in 38/40 (95 %), SAP5 were detected in 30/40 (75 %), SAP6 in 23/40 (57.5 %) of C. albicans strains isolated from blood cultures. SAP1-SAP3 were detected in 37 of 40 (92.5 %), SAP4 were detected in 3/40 (7.5 %), SAP5 in 3/40 (7.5 %), SAP6 in 5/40 (12.5 %) of C. albicans strains isolated from vaginal swab cultures. Sap 1, Sap2 and Sap3 isoenzymes were found to be related to the vaginopathic potential of C. albicans; Sap4, Sap5 and Sap6 isoenzymes were found to be correlated with systemic infections.