Adverse impact of hyperferritinemia and transfusion dependency on treatment success in myelodysplastic syndrome


Cakar M. K. , YEGİN Z. A. , Baysal N. A. , Altindal S., Pamukcuoglu M., ÇELİK B. , ...More

TRANSFUSION AND APHERESIS SCIENCE, vol.48, no.3, pp.397-401, 2013 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 48 Issue: 3
  • Publication Date: 2013
  • Doi Number: 10.1016/j.transci.2013.04.025
  • Title of Journal : TRANSFUSION AND APHERESIS SCIENCE
  • Page Numbers: pp.397-401

Abstract

Background: Myelodysplastic syndrome (MDS) is characterized by peripheral cytopenias and dysplasia in one or more cell lines in the bone marrow. A significant proportion of patients require blood product support due to symptomatic anemia and/or thrombocytopenia during the course of their disease. This retrospective study was planned to evaluate the transfusion requirement of MDS patients and the role of ferritin in predicting transfusion requirement and response to treatment.