Adverse impact of hyperferritinemia and transfusion dependency on treatment success in myelodysplastic syndrome

Cakar M. K., YEGİN Z. A., Baysal N. A., Altindal S., Pamukcuoglu M., ÇELİK B., ...Daha Fazla

TRANSFUSION AND APHERESIS SCIENCE, cilt.48, sa.3, ss.397-401, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 48 Sayı: 3
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1016/j.transci.2013.04.025
  • Dergi Adı: TRANSFUSION AND APHERESIS SCIENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.397-401
  • Anahtar Kelimeler: Myelodysplastic syndrome, Ferritin, Transfusion, Prognosis, Treatment, QUALITY-OF-LIFE, SERUM FERRITIN, MYELOID NEOPLASMS, IRON OVERLOAD, MDS, PROGNOSIS, DIAGNOSIS, ANEMIA
  • Gazi Üniversitesi Adresli: Evet

Özet

Background: Myelodysplastic syndrome (MDS) is characterized by peripheral cytopenias and dysplasia in one or more cell lines in the bone marrow. A significant proportion of patients require blood product support due to symptomatic anemia and/or thrombocytopenia during the course of their disease. This retrospective study was planned to evaluate the transfusion requirement of MDS patients and the role of ferritin in predicting transfusion requirement and response to treatment.