Comparative evaluation of Trichosporon asahii susceptibility using ASTY colorimetric microdilution and CLSI M27-A2 broth microdilution reference methods


Creative Commons License

Kalkanci A., Mekha N., Poonwan N., Makimura K., Sugita T.

MICROBIOLOGY AND IMMUNOLOGY, vol.52, no.9, pp.435-439, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 52 Issue: 9
  • Publication Date: 2008
  • Doi Number: 10.1111/j.1348-0421.2008.00056.x
  • Journal Name: MICROBIOLOGY AND IMMUNOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.435-439
  • Gazi University Affiliated: Yes

Abstract

The in vitro activity of AMPH-B, 5-FC, FLCZ, MCZ, ITCZ, and VRCZ against 50 isolates of T. asahii was determined using CLSI M27-A2 microdilution and ASTY colorimetric methods. Observed agreement ranged from 96 to 100% according to the drug. Overall, the agreement between two methods was 97.7%. The ASTY colorimetric method was thus determined to be comparable to the CLSI reference method when testing the susceptibility of T. asahii to a variety of antifungal agents.