Protection from cyclophosphamide-induced ovarian damage with bone marrow-derived mesenchymal stem cells during puberty


Kilic S., Pinarli F., Ozogul C., Tasdemir N., Sarac G. N. , Delibasi T.

GYNECOLOGICAL ENDOCRINOLOGY, cilt.30, sa.2, ss.135-140, 2014 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 30 Konu: 2
  • Basım Tarihi: 2014
  • Doi Numarası: 10.3109/09513590.2013.860127
  • Dergi Adı: GYNECOLOGICAL ENDOCRINOLOGY
  • Sayfa Sayıları: ss.135-140

Özet

Objective: In female cancer survivors, the accelerated loss of primordial follicles may lead to premature ovarian failure. We investigated the protective effects of bone marrow derived mesenchymal stem cells (BMMSC) and gonadotropin releasing hormone analogue (GnRHa) against chemotherapeutic-induced ovarian toxicity in a rat model.