Body Ownership, Sensorimotor Integration and Motor Cortical Excitability: A TMS Study About Rubber Hand Illusion.


Alaydin H. C., Cengiz B.

Neuropsychologia, vol.161, pp.107992, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 161
  • Publication Date: 2021
  • Doi Number: 10.1016/j.neuropsychologia.2021.107992
  • Journal Name: Neuropsychologia
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus, Academic Search Premier, PASCAL, AgeLine, BIOSIS, EMBASE, Linguistics & Language Behavior Abstracts, MEDLINE, MLA - Modern Language Association Database, Psycinfo
  • Page Numbers: pp.107992
  • Keywords: Rubber hand illusion, Sensorimotor integration, Transcranial magnetic stimulation, Short latency afferent inhibition, Short interval intracortical inhibition, Intracortical facilitation, LATENCY AFFERENT INHIBITION, CIRCUITS, CORTEX, ACTIVATION, DISEASE, AGENCY
  • Gazi University Affiliated: Yes

Abstract

Objective: The Rubber Hand Illusion (RHI) manipulates body ownership experimentally and helps investigate the related neurophysiological processes. This study aimed to evaluate motor cortex excitability that hypothesized changed due to illusion. Method: Twenty-one healthy (twelve male, nine female), right-handed volunteers aged between 25 and 50 years were recruited to the study. Short-Latency Afferent Inhibition (SAI) was evaluated by transcranial magnetic stimulation (TMS) given with a figure-of-eight-shaped coil from the left motor cortex, 21 ms after peripheral electrical stimulation. Short-Interval Intracortical Inhibition (SICI) and Intracortical Facilitation (ICF) were investigated using a paired-pulse TMS at interstimulus intervals (ISI) of 1, 2.5, 3 ms and 15, 20, 25 ms, respectively. We used custom-made illusion setups for TMS paradigms. SAI, SICI and ICF was evaluated before, during and 15 min after the RHI. Results: Results of the study revealed significantly high SAI during illusion compared to pre-illusion, but no difference was found between post-illusion 15th minutes and control measurements. Significantly reduced SICI at 2.5 and 3 ms ISI obtained during illusion, while RHI did not affect SICI at 1 ms ISI and ICF. Significance: Body ownership illusion modulates the motor cortex excitability, possibly through altered sensory processing and sensorimotor integration.