Use of long-term combined therapy with inhaled iloprost and oral sildenafil in an adult patient with Eisenmenger syndrome

Okyay K., CEMRİ M. , Boyaci B. , Yalcin R., Cengel A.

Cardiology in Review, vol.13, no.6, pp.312-314, 2005 (Journal Indexed in SCI Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 6
  • Publication Date: 2005
  • Doi Number: 10.1097/01.crd.0000181618.29506.1e
  • Title of Journal : Cardiology in Review
  • Page Numbers: pp.312-314


Eisenmenger syndrome is characterized by elevated pulmonary vascular resistance and right-to-left shunting of blood through a systemic to pulmonary circulation connection. Treatment requires either lung transplantation with intracardiac repair or heart-lung transplantation. There are inadequate data regarding treatment alternatives when the patient is not a candidate for surgery. In this article, we report on the case of a 68-year-old woman with Eisenmenger syndrome related to congenital heart disease who was treated with inhaled iloprost and oral sildenafil for 2 years. Copyright © 2005 by Lippincott Williams & Wilkins.