Extracorporeal Photochemotherapy: Mechanism of Action, Side Effects, Dermatological Indications


ADIŞEN E. , Guerer M. A.

TURKDERM-TURKISH ARCHIVES OF DERMATOLOGY AND VENEROLOGY, cilt.42, ss.39-44, 2008 (SCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 42 Konu: 2
  • Basım Tarihi: 2008
  • Dergi Adı: TURKDERM-TURKISH ARCHIVES OF DERMATOLOGY AND VENEROLOGY
  • Sayfa Sayıları: ss.39-44

Özet

Extracorporeal photochemotherapy is an extracorporeal form of photochemotherapy with 8-methoxypsoralen and ultraviolet A radiation. Evidence suggests that there may be a potential role for extracorporeal photochemotherapy in the therapy of T-cell-mediated diseases and certain autoimmune diseases resistant to conventional therapy. Extracorporeal photochemotherapy has been used to treat various diseases, such as cutaneous T-cell lymphoma, bullous disorders, connective tissue disorders, atopic dermatitis, lichen planus, psoriasis vulgaris and in the suppression of graft versus host disease. The exact mechanism of this treatment is not known. This review focuses on the dermatological diseases treated with extracorporeal photochemotherapy and side effects of it. (Turkderm 2008; 42: 39-44)