Hepatic and renal tissue selenium levels in a mouse model of candidiasis

Kalkanci A., Bukan N., Sancak B., Kustimur S.

TRACE ELEMENTS AND ELECTROLYTES, vol.22, no.4, pp.272-276, 2005 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 22 Issue: 4
  • Publication Date: 2005
  • Doi Number: 10.5414/tep22272
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.272-276
  • Gazi University Affiliated: Yes


Objective: Candidemia is a form of sepsis resulting in a complicated inflammatory response in living organisms. There is no sufficient data about selenium levels in candidiasis. Methods: Selenium levels were analyzed by atomic absorption spectrophotometry in different organs of mouse model of candidiasis. Results: We found that selenium levels increased in hepatic tissue of the mice (1045.9 +/- 166.29 ng/ml), while they decreased in renal tissue (518.48 +/- 258.18 ng/ml) when compared with control groups (p > 0.001). Conclusions: This can be explained by the different selenium uptake of the metabolic pathways in renal and hepatic tissues.