Effects of platelet-activating factor on nitrergic transmission in rabbit corpus cavernosum

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Ozger S., Barun S., Vural I., Ercan Z., Sarioglu Y.

INTERNATIONAL JOURNAL OF UROLOGY, cilt.12, sa.6, ss.570-573, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 12 Sayı: 6
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1111/j.1442-2042.2005.01109.x
  • Dergi Adı: INTERNATIONAL JOURNAL OF UROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.570-573
  • Anahtar Kelimeler: nitric oxide, platelet activating factor, rabbit corpus cavernosum, NITRIC-OXIDE, RELAXATION
  • Gazi Üniversitesi Adresli: Evet

Özet

Aim: The information currently available suggests that nonadrenergic noncholinergic (NANC) transmitters, particularly nitric oxide, are involved in the relaxation of penile erectile tissues. Platelet-activating factor (PAF) is a chemical mediator and is involved in many physiological and pathophysiological events. It is well known that several of the vascular actions of PAF are mediated by the generation of nitric oxide. We designed this study to test the hypothesis that PAF has an effect on NANC responses in rabbit corpus cavernosum strips.