Permeability and its susceptibility to changes with time or exposure to chemicals are major factors in selection of earthen liners for use in hazardous liquid-waste containment systems, Earthen liners often consist of mixtures including both granular soil and fine matrix. Six different solid mixtures were tested to investigate the influence of hazardous liquid waste on their permeability. The granular part of the mixtures included sand and crushed natural zeolite, whereas the matrix was composed of bentonite and microcement. Highly acidic solutions, bases, leather industry leachate and municipal waste leachate were used as permeants. Of the mixtures tested, only two mixtures performed well against the attack of chemicals. The testing method was the falling head system with the compaction mold permeameter. The period of experiments varied from two to eight weeks.