Effects of sildenafil treatment on patients with Peyronie's disease and erectile dysfunction


Ozturk U., Yesil S., Goktug H. N. G. , Gucuk A., Tuygun C., Sener N. C. , ...More

IRISH JOURNAL OF MEDICAL SCIENCE, vol.183, no.3, pp.449-453, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 183 Issue: 3
  • Publication Date: 2014
  • Doi Number: 10.1007/s11845-013-1036-5
  • Journal Name: IRISH JOURNAL OF MEDICAL SCIENCE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.449-453
  • Keywords: Peyronie's disease, Phosphodiesterase isoenzyme inhibitors, Sildenafil, Treatment, NITRIC-OXIDE SYNTHASE, MEN, INHIBITION, MANAGEMENT, ULTRASOUND, CITRATE, SYSTEM
  • Gazi University Affiliated: Yes

Abstract

It has been shown on experimental rat models that type 5-phosphodiesterase isoenzyme (PDE5) inhibitors have anti-fibrotic effects for Peyronie's disease (PD); however, this issue has not been addressed clinically. The aim of this study was to document the effects of PDE5 inhibitors used for erectile dysfunction (ED) seen in PD patients on the main course of the PD clinically.