Metastasis from lung cancer presenting as pyogenic granuloma in the lower gingiva Gingivalni eruptivni hemangiom kao metastaza karcinoma pluća

Shuibat A. M., BARIŞ E., Karan B., Yetişyiǧi T.

Acta Stomatologica Croatica, vol.46, no.4, pp.307-311, 2012 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 46 Issue: 4
  • Publication Date: 2012
  • Journal Name: Acta Stomatologica Croatica
  • Journal Indexes: Scopus
  • Page Numbers: pp.307-311
  • Keywords: Adenocarcinoma, Gingival neoplasms, Granuloma, Lung neoplasms, Neoplasm metastasis, Pyogenic, Secondary
  • Gazi University Affiliated: Yes


Metastatic tumors involve the oral cavity, and the most common primary sites are lungs and breasts. Lung cancer metastasis to the gingiva is quite unusual; metastases to the jaw bone, especially to the posterior mandible are more common. Because of their rarity, metastases to oral cavity are challenging to diagnose and difficult to treat. They often have vague symptoms that mimic dental infection. In this paper, a case of a patient with lung cancer, who developed metastasis to the oral soft tissue, is presented. After the detection of gingival metastasis, the patient underwent complete general examination and CT scans which detected another metastasis in the left clavicular bone. The role of dental team in diagnosis and directing the treatment of these patients is important. On the other hand, the importance of histomorphology and immunohistochemical techniques especially cytokeratin 7, cytokeratin 20 and TTF1 in the final diagnosis should also be emphasized.