Comparison of the tocolytic effects of ritodrine and Ca++ channel blockers on serum oestradiol and progesterone levels

Tosun F., Gonenc A., Simsek B.

TURKISH JOURNAL OF VETERINARY & ANIMAL SCIENCES, cilt.27, sa.2, ss.417-423, 2003 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 2
  • Basım Tarihi: 2003
  • Dergi Adı: TURKISH JOURNAL OF VETERINARY & ANIMAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.417-423
  • Gazi Üniversitesi Adresli: Hayır

Özet

Experimental pregnancy was induced with gonadal steroids in in vivo ovariectomized rats. Conditions for premature delivery were established by giving a salt-rich diet and administering oxytocin to induce high-risk pregnancy. In order to avoid early delivery, a betamimetic ritodrine and the Ca++ channel blockers nitrendipine and nicardipine were administered to three separate groups. The effects of these three tocolytic agents were examined by determining serum oestradiol and progesterone levels. Additionally, systolic blood pressure was measured and tachycardia was observed.