A novel fluorescence turn-on coumarin-pyrazolone based monomethine probe for biothiol detection


Babur B., SEFEROĞLU N. , Ocal M., Sonugur G., AKBULUT H., SEFEROĞLU Z.

TETRAHEDRON, cilt.72, sa.30, ss.4498-4502, 2016 (SCI İndekslerine Giren Dergi) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 72 Konu: 30
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1016/j.tet.2016.06.008
  • Dergi Adı: TETRAHEDRON
  • Sayfa Sayıları: ss.4498-4502

Özet

A coumarin-pyrazolone monomethine based turn-on fluorescence ratiometric probe C-3 for selective detection of cysteine (Cys) and glutathione (GSH) is reported. It exhibits OFF-ON states and is more sensitive to GSH in aqueous solution neutral and basic pH. The ON state is due to the inhibition of intramolecular charge transfer (ICT) process between pyrrole and pyrazolone moieties. (C) 2016 Elsevier Ltd. All rights reserved.