Methimazole protects lungs during hepatic ischemia-reperfusion injury in rats: An effect not induced by hypothyroidism

Tutuncu T., Demirci C., Gozalan U., Yuksek Y. N., Bilgihan A., Kama N. A.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, cilt.22, sa.5, ss.704-709, 2007 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22 Sayı: 5
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1111/j.1440-1746.2006.04202.x
  • Dergi Adı: JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.704-709
  • Anahtar Kelimeler: hypothyroidism, ischemia-reperfusion, lung, malondialdehyde, methimazole, MULTIPLE ORGAN FAILURE, LONG-TERM TREATMENT, ANTITHYROID DRUG, LIVER ISCHEMIA, DAMAGE, ISCHEMIA/REPERFUSION, RADICALS, PROPYLTHIOURACIL, INHIBITION, CIRRHOSIS
  • Gazi Üniversitesi Adresli: Evet

Özet

Background: Hepatic ischemia-reperfusion injury may lead to remote organ failure with mortal respiratory dysfunction. The aim of the present study was to analyze the possible protective effects of methimazole on lungs after hepatic ischemia-reperfusion injury.