Methimazole protects lungs during hepatic ischemia-reperfusion injury in rats: An effect not induced by hypothyroidism


Tutuncu T., Demirci C., Gozalan U., Yuksek Y. N. , Bilgihan A., Kama N. A.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, vol.22, no.5, pp.704-709, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 22 Issue: 5
  • Publication Date: 2007
  • Doi Number: 10.1111/j.1440-1746.2006.04202.x
  • Journal Name: JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.704-709
  • Keywords: hypothyroidism, ischemia-reperfusion, lung, malondialdehyde, methimazole, MULTIPLE ORGAN FAILURE, LONG-TERM TREATMENT, ANTITHYROID DRUG, LIVER ISCHEMIA, DAMAGE, ISCHEMIA/REPERFUSION, RADICALS, PROPYLTHIOURACIL, INHIBITION, CIRRHOSIS
  • Gazi University Affiliated: No

Abstract

Background: Hepatic ischemia-reperfusion injury may lead to remote organ failure with mortal respiratory dysfunction. The aim of the present study was to analyze the possible protective effects of methimazole on lungs after hepatic ischemia-reperfusion injury.