Pulmonary Involvement of Diffuse Large B-cell Lymphoma with Cavitary Lesions

Kara İ., Yıldırım F., Berber E., Öcal R., Yegin Z. A., Türkoğlu M., ...Daha Fazla

American Journal of Medical Sciences and Medicine, cilt.4, sa.2, ss.47-49, 2016 (Hakemli Dergi)

  • Yayın Türü: Makale / Vaka Takdimi
  • Cilt numarası: 4 Sayı: 2
  • Basım Tarihi: 2016
  • Dergi Adı: American Journal of Medical Sciences and Medicine
  • Derginin Tarandığı İndeksler: Index Copernicus
  • Sayfa Sayıları: ss.47-49
  • Gazi Üniversitesi Adresli: Evet

Özet

Abstract Diffuse large B-cell lymphoma (DLBCL) is the most common type of extranodal lymphoma. Typically disease occurs fastly growing nodal or extranodal masses with systemic symptoms. Pulmonary involvement may also occur in DLBCL. Here we present a DLBCL with cavitary lesions in the lung. A 59-year-old male was diagnosed with DLBCL through an endoscopic gastric biopsy that was performed 1.5 years ago. After six course of R-CHOP chemotherapy, the relaps of disease was confirmed with mediastinoscopy. Despite two courses of RICE chemotherapy and one course of R-BAB therapies, the patient was admitted to the intensive care unit with shortness of breath and tachypnea. Thorax computed tomography showed a mass lesion that enclosed and narrowed the right major bronchus and multiple lesions with cavitation. The infections were excluded with bronchoscopy. The patient received pulse steroid therapy, radiotherapy and three courses of Hyper-CVAD chemotherapy. In the control thorax CT, cavitary lesions got smaller, respiratory insufficiency of patient improved. When pulmonary cavitary lesions are observed in patients under follow-up with the diagnosis of lymphoma, the pulmonary involvement of lymphoma should also be considered in addition to the infectious agents.