Novel Piperazine Amides of Cinnamic Acid Derivatives as Tyrosinase Inhibitors

GÜR MAZ, ZEHRA; ŞENOL DENİZ, FATMA; Shekfeh, Suhaib; ERDOĞAN ORHAN, İLKAY; BANOĞLU, ERDEN; ÇALIŞKAN, BURCU

doi:10.2174/1570180815666180420105652

Novel Piperazine Amides of Cinnamic Acid Derivatives as Tyrosinase Inhibitors

GÜR MAZ Z. T., ŞENOL DENİZ F. S., Shekfeh S., ERDOĞAN ORHAN İ., BANOĞLU E., ÇALIŞKAN B.

LETTERS IN DRUG DESIGN & DISCOVERY, cilt.16, sa.1, ss.36-44, 2019 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 16 Sayı: 1
Basım Tarihi: 2019
Doi Numarası: 10.2174/1570180815666180420105652
Dergi Adı: LETTERS IN DRUG DESIGN & DISCOVERY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.36-44
Anahtar Kelimeler: Ferulic acid, cinnamic acid, piperazine, tyrosinase, docking, huntington's diseases, MUSHROOM TYROSINASE, ANALOGS, DOCKING, AGENTS, DRUGS
Gazi Üniversitesi Adresli: Evet

Özet

Background: A series of novel cinnamic acid piperazine amide derivatives has been designed and synthesized, and their biological activities were also evaluated as potential tyrosinase inhibitors.