Novel Piperazine Amides of Cinnamic Acid Derivatives as Tyrosinase Inhibitors

GÜR MAZ Z. T., ŞENOL DENİZ F. S., Shekfeh S., ERDOĞAN ORHAN İ., BANOĞLU E., ÇALIŞKAN B.

LETTERS IN DRUG DESIGN & DISCOVERY, cilt.16, sa.1, ss.36-44, 2019 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 16 Sayı: 1
  • Basım Tarihi: 2019
  • Doi Numarası: 10.2174/1570180815666180420105652
  • Dergi Adı: LETTERS IN DRUG DESIGN & DISCOVERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.36-44
  • Anahtar Kelimeler: Ferulic acid, cinnamic acid, piperazine, tyrosinase, docking, huntington's diseases, MUSHROOM TYROSINASE, ANALOGS, DOCKING, AGENTS, DRUGS
  • Gazi Üniversitesi Adresli: Evet

Özet

Background: A series of novel cinnamic acid piperazine amide derivatives has been designed and synthesized, and their biological activities were also evaluated as potential tyrosinase inhibitors.