Comparison of hippocampal interleukin-6 immunoreactivity after exhaustive exercise in both exercise-trained and untrained rats

Aral L. A., Pinar L., Goktas G., Deveden E. Y., Erdogan D.

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.44, sa.4, ss.560-568, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 44 Sayı: 4
  • Basım Tarihi: 2014
  • Doi Numarası: 10.3906/sag-1305-23
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.560-568
  • Anahtar Kelimeler: Exhaustive exercise, hippocampus, interleukin-6, SKELETAL-MUSCLE, VOLUNTARY EXERCISE, ADIPOSE-TISSUE, INFLAMMATION, CYTOKINES, HUMANS, BRAIN, MICE, IL-6, MECHANISMS
  • Gazi Üniversitesi Adresli: Evet

Özet

Background/aim: Exhaustive exercise is a strong stress factor and can impact cytokine production in the brain. Interleukin-6 (IL-6) is produced in greater amounts than any other cytokine in response to exercise, and its effects are closely related to both exercise duration and intensity. In this study, we measured the differences between the amount of IL-6 reactivity of the hippocampus after an exhaustive session of running in long-term exercise-trained and untrained rats.