Akademik Veri Yönetim Sistemi
Plant Biosystems, cilt.160, sa.1, 2026 (SCI-Expanded, Scopus)
Wild edible mushrooms are valued for their culinary appeal, health benefits, and bioactive compounds. This study investigates the in vitro cell growth inhibitory potential and biological activities of six wild edible mushroom species: Armillaria mellea, Craterellus cornucopioides, Laccaria laccata, Lepista nuda, Leucoagaricus leucothites, and Lycoperdon molle from the Eastern Black Sea coast of Türkiye. The water extract of L. molle exhibited the highest cytotoxicity against HepG2 cells, while L. nuda showed notable effectiveness with its methanol extract. DPPH radical scavenging activity was most pronounced in methanol extract of L. molle and water extract of A. mellea. Additionally, L. molle displayed superior reducing power and phenolic contents compared to the other mushrooms. Notably, L. nuda had the highest levels of β-carotene and lycopene among the methanol extracts. Antibacterial assays identified L. nuda as particularly effective against various bacterial strains, with minimum inhibitory concentrations highlighting L. nuda and C. cornucopioides as the most potent antimicrobial extracts. This study underscores these mushrooms' potential as sources of bioactive compounds with antioxidant, cytotoxic, and antimicrobial properties, particularly highlighting L. nuda and L. molle for their high cytotoxicity, robust antioxidant activity, and antibacterial efficacy. These findings support further research into their therapeutic applications and medicinal value.