In this study, production routes of medical 110,111 In radionuclides produced by 110Cd(p,n)110In, 111Cd(p, 2n) 110In, 112Cd(p, 3n) 110In, 107Ag(a, n)110In, 109Ag(a, 3n)110In, 111Cd(P, n)111In, 112Cd(p, 2n)111In, 113Cd(p, 3n)111In, 114Cd(P, 4n)111In, 109Ag(a, 2n) 111In, 107Ag(a, y)111In and 113In(n, 3n)111In reactions have been investigated up to 70 MeV incident particle energy. In these calculations, the preequilibrium and equilibrium effects have been investigated. The pre-equilibrium calculations involve the geometry dependent hybrid model and the cascade exciton model. The full exciton model has also been used to investigate the pre-equilibrium direct effects. Equilibrium effects are calculated according to the Weisskopf-Ewing model. The calculated results are compared with the experimental data taken from the literature. © Carl Hanser Verlag,.