Neuroprotective effects of allocryptopine-rich alkaloid extracts against oxidative stress-induced neuronal damage

Niğdelioğlu Dolanbay S., Kocanci F. G., Aslım B.

BIOMEDICINE & PHARMACOTHERAPY, cilt.140, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 140
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1016/j.biopha.2021.111690
  • Dergi Adı: BIOMEDICINE & PHARMACOTHERAPY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, EMBASE, Food Science & Technology Abstracts, MEDLINE, Veterinary Science Database, Directory of Open Access Journals
  • Anahtar Kelimeler: Alkaloid, Allocryptopine, Cell cycle, Neuronal apoptosis, Neuroprotective effect, Oxidative stress, PC12 CELLS, HYDROGEN-PEROXIDE, INDUCED APOPTOSIS, H2O2-INDUCED APOPTOSIS, INHIBITORY-ACTIVITY, PCR DATA, GC-MS, PROTECTS, CYCLE, PAPAVERACEAE
  • Gazi Üniversitesi Adresli: Evet

Özet

Background: Oxidative stress is a significant feature in the pathomechanism of neurodegenerative diseases. Thus, the search for an effective and safe novel antioxidant agent with neuroprotective properties has increased the interest in medicinal plant products as a bioactive phytochemical source. However, little is known about the potential effects of the medically important Glaucium corniculatum as a natural antioxidant.