Synthesis and chemical transformations of 3-acetyl-4-hydroxyquinolin-2(1H)-one and its N-substituted derivatives: bird's eye view


Abdou M. M. , SEFEROĞLU Z. , Fathy M., Akitsu T., Koketsu M., Kellow R., ...More

RESEARCH ON CHEMICAL INTERMEDIATES, vol.45, no.3, pp.919-934, 2019 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Review
  • Volume: 45 Issue: 3
  • Publication Date: 2019
  • Doi Number: 10.1007/s11164-018-3652-1
  • Title of Journal : RESEARCH ON CHEMICAL INTERMEDIATES
  • Page Numbers: pp.919-934

Abstract

The chemistry of 3-acetyl-4-hydroxyquinolin-2(1H)-ones has attracted increased attention in both synthetic organic and medicinal chemistry, as numerous advancements in the use of this family of important compounds seems to be of considerable value. This account summarizes the results from the literature focusing on synthesis of 3-acetyl-4-hydroxyquinolin-2(1H)-ones as well as their reactions are also discussed.