A new definition of aspirin non-responsiveness by Platelet Function Analyzer-100 (TM) and its predictors

Abaci A., Caliskan M., Bayram F., Yilmaz Y., Cetin M., Unal A., ...More

PLATELETS, vol.17, no.1, pp.7-13, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 1
  • Publication Date: 2006
  • Doi Number: 10.1080/09537100500163358
  • Journal Name: PLATELETS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.7-13
  • Keywords: aspirin, non-responsiveness, platelet, function, IN-VITRO, ACETYLSALICYCLIC ACID, RESISTANCE, FAILURE, STROKE, ASA
  • Gazi University Affiliated: No

Abstract

Background: Aspirin non-responsiveness has been described as having a normal closure time (CT) by platelet function analyzer (PFA)-100 assay despite confirmed treatment with aspirin. There is no standard definition of aspirin non-responsiveness by PFA-100, with a variety of cut-off values having been used. We proposed an alternative definition of aspirin non-responsiveness by PFA-100 assay.