Nursing Open, cilt.13, sa.5, ss.1-14, 2026 (SCI-Expanded, SSCI, Scopus)
ABSTRACTAim: This study evaluated the effect of a virtual simulation game (VSG) on the development of nursing students' knowledge andskills related to the prevention of Catheter-Associated Urinary Tract Infection (CAUTI).Design: A parallel group randomized controlled trial. The study is registered with ClinicalTrials.gov under the numberNCT05309317.Methods: This study was completed by 75 students (38 simulation and 37 control). Students' knowledge and skill levels wereassessed prior to the training. A training on CAUTI prevention was presented to the students. After randomization, the VSGgroup accessed VSG for 7 days. Following the intervention, students' knowledge and skill levels were measured using post-testassessments.Results: As a result of the study, the post-test mean scores for knowledge and skills in the VSG group were statistically higherthan those in the control group (p < 0.05). The results of the study indicate that VSG was an interesting, stimulating, fun, practi-cal and accessible educational approach for university students.Conclusions: The use of a well-designed VSG application as a teaching and learning strategy contributed to the development ofstudents' knowledge and skills in CAUTI prevention. It is recommended to use VSG as a preliminary or complementary methodto traditional face-to-face simulation and clinical applications.Patient or Public Contribution: The game's judgements, having no impact on real life, safeguard patient safety and enhanceclinical skills.Trial Registration: ClinicalTrials.gov: NCT05309317