SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, vol.65, pp.89-93, 2019 (Journal Indexed in SCI)
Article / Article
Title of Journal :
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
Epilepsy, Dynamic thiol/disulphide homeostasis, Valproic acid, Carbamazepine, OXIDATIVE STRESS, LIPID-PEROXIDATION, VALPROIC ACID, SUPEROXIDE-DISMUTASE, TRACE-ELEMENTS, ANTIOXIDANT, GLUTATHIONE, CARBAMAZEPINE, EPILEPTOGENESIS, SYSTEMS
Purpose: Anti-epileptic drugs have been widely used in children with epilepsy. Although several studies have investigated the role of oxidative stress and the effects of antiepileptic drugs on several oxidative markers in epilepsy, adequate information is not available on this issue. This study aimed to investigate the changes in thiol disulphide homeostasis in children with epilepsy under two commonly prescribed AED monotherapies, carbamazepine and valproic acid.