Low Serum Vitamin D Levels Are Associated with Severe Histological Features and Poor Response to Therapy in Patients with Autoimmune Hepatitis

Efe, Cumali; KAV, TAYLAN; Aydin, Cisel; Cengiz, Mustafa; Imga, Narin; Purnak, Tugrul; Smyk, Daniel; Torgutalp, Murat; Turhan, Turan; Ozenirler, Seren; Ozaslan, Ersan; Bogdanos, Dimitrios

doi:10.1007/s10620-014-3267-3

Low Serum Vitamin D Levels Are Associated with Severe Histological Features and Poor Response to Therapy in Patients with Autoimmune Hepatitis

Atıf İçin Kopyala

Efe C., KAV T., Aydin C., Cengiz M., Imga N. N., Purnak T., ...Daha Fazla

DIGESTIVE DISEASES AND SCIENCES, cilt.59, sa.12, ss.3035-3042, 2014 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 59 Sayı: 12
Basım Tarihi: 2014
Doi Numarası: 10.1007/s10620-014-3267-3
Dergi Adı: DIGESTIVE DISEASES AND SCIENCES
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.3035-3042
Anahtar Kelimeler: Autoimmune hepatitis, Vitamin D, Therapy response, Noninvasive marker, Fibrosis, LIVER-DISEASE, D DEFICIENCY, DIAGNOSIS
Gazi Üniversitesi Adresli: Evet

Özet

Background and Aim 25-Hydroxyvitamin D [25(OH)D] has an important role in fibrosis progression and inflammatory response in patients with various etiologies of chronic liver disease. However, its influence on autoimmune hepatitis (AIH) has not been investigated. We evaluated the association of serum 25(OH)D levels with clinical, biochemical and histological features and response to therapy in AIH.