Low Serum Vitamin D Levels Are Associated with Severe Histological Features and Poor Response to Therapy in Patients with Autoimmune Hepatitis


Efe C., KAV T., Aydin C., Cengiz M., Imga N. N. , Purnak T., ...More

DIGESTIVE DISEASES AND SCIENCES, vol.59, no.12, pp.3035-3042, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 59 Issue: 12
  • Publication Date: 2014
  • Doi Number: 10.1007/s10620-014-3267-3
  • Journal Name: DIGESTIVE DISEASES AND SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.3035-3042
  • Keywords: Autoimmune hepatitis, Vitamin D, Therapy response, Noninvasive marker, Fibrosis, LIVER-DISEASE, D DEFICIENCY, DIAGNOSIS
  • Gazi University Affiliated: Yes

Abstract

Background and Aim 25-Hydroxyvitamin D [25(OH)D] has an important role in fibrosis progression and inflammatory response in patients with various etiologies of chronic liver disease. However, its influence on autoimmune hepatitis (AIH) has not been investigated. We evaluated the association of serum 25(OH)D levels with clinical, biochemical and histological features and response to therapy in AIH.