© 2022 Informa UK Limited, trading as Taylor & Francis Group.Millimeter-wave (mm-Wave) spectrum is an essential enabler to the fifth generation (5G) wireless technology. Humans are one of the most noticeable blockers that cause temporal variation in indoor radio channels. This paper presents human blockage measurements at 28 GHz, with several humans of different sizes. The effect of the crossing orientations of the human bodies is investigated for three different transmitter heights. A human blockage model based on the Fresnel diffraction scheme is shown to be applicable in estimating the human blockage loss in indoor radio links considering various body sizes, different crossing orientations, and different transmitter heights. The findings reported in this paper could help improve indoor radio channel models at 28 GHz bands for 5G technologies considering the presence of human body blockages.