Tall buildings, the indispensable elements of the cities evolved in order to respond to rapidly increasing population and urbanization from the beginning of the 20th century, are quickly emerging to the foreground with their unique designs in both load-bearing systems and energy and resource management. Their sensitivity to lateral loads due to wind and earthquakes has inadvertedly made an important contribution to the development of advanced construction technologies in tall structures. The main aim of the study is to discuss the load-bearing systems, which has an effect on the shaping of the function in architectural design, combined with the concept of sustainability, which holds a significant place in the discourse of modern day. In this context, the buildings of Norman Foster, who successfully combines his engineering and architectural identities in his work and synthesizing advanced load-bearing systems within sustainable design principles, have been examined. These buildings, examined via criteria such as construction system, material, structural form, lateral load resistance, the utility core, innovation, energy efficiency and effective use of water, are prime examples of 21st century tall building construction, safe and respectful to environment via the meeting between form and function. As a result, it is believed that this study will be an archival feature in discussing architectural design and structural design criteria together. It has been emphasized to develop architectural design solutions integrating technological, aesthetic and environmental sensitivities.