Assessment of left ventricular diastolic function by Doppler tissue imaging in children with end-stage renal disease

Saygili A., Yildirim S., Cengiz N., Uslu Y., Tokel K., Saatci U.

ACTA PAEDIATRICA, vol.94, no.8, pp.1055-1059, 2005 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 94 Issue: 8
  • Publication Date: 2005
  • Doi Number: 10.1080/08035250510025798
  • Journal Name: ACTA PAEDIATRICA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1055-1059
  • Gazi University Affiliated: No


Aim: To evaluate left ventricular (LV) diastolic function in children with end-stage renal disease ( ESRD) using conventional pulsed-Doppler echocardiography and Doppler tissue imaging (DTI), and to compare the findings with these two modalities. Methods: Twenty-four children with ESRD and 22 healthy age- and sex-matched control subjects were assessed with conventional Doppler echocardiography and DTI. The scans of the renal disease patients were done after a dialysis session. Parameters related to LV systolic and diastolic function were compared in the ESRD and control groups. Results: The ESRD patients had lower mean mitral E/A ratio both according to conventional Doppler echocardiography and TDI than the control subjects. The ESRD group also had significantly longer isovolumetric relaxation time (116 +/- 31 ms vs 97 +/- 3.1 ms, respectively; p<0.001), and significantly longer deceleration time (235 +/- 44 ms vs 202 +/- 35 ms, respectively; p<0.01) than the control group.