Major bioactive compounds from Java Plum seeds: An investigation of its extraction procedures and clinical effects

Das G., Nath R., Talukdar A. D., Ağagündüz D., Yılmaz B., Capasso R., ...Daha Fazla

PLANTS, cilt.12, sa.6, ss.1214-1236, 2023 (SCI-Expanded)

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 12 Sayı: 6
  • Basım Tarihi: 2023
  • Dergi Adı: PLANTS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Agricultural & Environmental Science Database, BIOSIS, CAB Abstracts, Food Science & Technology Abstracts, Veterinary Science Database, Directory of Open Access Journals
  • Sayfa Sayıları: ss.1214-1236
  • Gazi Üniversitesi Adresli: Evet

Özet

Java plum is widely recognized as a plant with valuable medical properties, originating from Indonesia and India and distributed globally in the tropics and sub-tropics. The plant is rich in alkaloids, flavonoids, phenyl propanoids, terpenes, tannins, and lipids. The phytoconstituents of the plant seeds possess various vital pharmacological activities and clinical effects including its antidiabetic potential. The bioactive phytoconstituents of java plum seeds includes jambosine, gallic acid, quercetin, β-sitosterol, ferulic acid, guaiacol, resorcinol, p-coumaric acid, corilagin, ellagic acid, catechin, epicatechin, tannic acid, 4,6 hexahydroxydiphenoylglucose, 3,6-hexahydroxy diphenoylglucose,1-galloylglucose, and 3-galloylglucose. Considering all the potential benifical effects of the major bioactive compounds of the seeds of this plant species, in the current investigation, the specific clinical effects and the mechanism of action of the major bioactive compounds along with the extraction procedure are discussed.