The use of a prostacyclin analog, iloprost, as an adjunct to uterus preservation with histidine-tryptophan-ketoglutarate solution.


Barun S., Ozat M., Gungor T., Demirogullari B., Sokmensuer L. K., Aksakal F. N., ...Daha Fazla

Transplantation proceedings, cilt.43, sa.5, ss.1998-2003, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 43 Sayı: 5
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1016/j.transproceed.2011.04.005
  • Dergi Adı: Transplantation proceedings
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1998-2003
  • Gazi Üniversitesi Adresli: Evet

Özet

Introduction. Although assisted reproductive techniques have made most causes of both male and female infertility treatable, uterine factor infertility is not able to therapy. Therefore, transplantation of the uterus has been suggested as a future possible cure. Organ preservation solutions seek to reduce reperfusion injury. Since iloprost is an antioxidant with cytoprotective properties, we investigated its potential positive effects in histidine-tryptophan-ketoglutarate (HTK) solution after 4 or 24 h cold storage period of the rat uterus.