Successful Treatment of Post-Covid-19 Severe Anca-Associated Vasculitis: Case Report

Ural Z., Yildirim S., ŞAHİN O. T., TOMAR V. B., ZELYURT N., Koc H., ...Daha Fazla

REVISTA DE NEFROLOGIA DIALISIS Y TRASPLANTE, cilt.46, sa.1, ss.31-36, 2026 (SCI-Expanded, Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 46 Sayı: 1
  • Basım Tarihi: 2026
  • Dergi Adı: REVISTA DE NEFROLOGIA DIALISIS Y TRASPLANTE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Fuente Academica Plus, EMBASE, Directory of Open Access Journals, DIALNET
  • Sayfa Sayıları: ss.31-36
  • Gazi Üniversitesi Adresli: Evet

Özet

Background: The SARS-CoV-2 pandemic has become a major global health concern. Kidney involvement in COVID-19 patients is common and associated with high mortality. Although acute tubular necrosis due to hemodynamic instability is the most frequent cause, other complex and destructive mechanisms related to cytokine storm and immune system activation have also been reported. Case presentation: We report a case of proteinase-3 antineutrophil cytoplasmic antibody (PR3-ANCA)-associated vasculitis presenting with severe pulmonary-renal syndrome, a rare and potentially fatal complication that occurred approximately two months after COVID-19 infection. Conclusions: While a causal relationship cannot be definitively established, immune dysregulation triggered by COVID-19 may have contributed to the development of ANCA-associated vasculitis (AAV). AAV is a serious disease, and prompt immunosuppressive therapy led to full recovery.