Adenosine deaminase, 5′ nucleotidase, xanthine oxidase, superoxide dismutase, and catalase activities in cancerous and noncancerous human laryngeal tissues

DURAK İ., Işik C. Ü., CANBOLAT O., Akyol Ö., Kavutçu M.

Free Radical Biology and Medicine, cilt.15, sa.6, ss.681-684, 1993 (Scopus) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Sayı: 6
  • Basım Tarihi: 1993
  • Doi Numarası: 10.1016/0891-5849(93)90174-s
  • Dergi Adı: Free Radical Biology and Medicine
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.681-684
  • Anahtar Kelimeler: CANCER, ADENOSINE DEAMINASE, 5' NUCLEOTIDASE, XANTHINE OXIDASE, SUPEROXIDE DISMUTASE, CATALASE, FREE RADICALS, HUMAN-EPIDERMIS, FREE-RADICALS, CARCINOMA, HEPATOMAS, SYSTEMS, DISEASE
  • Gazi Üniversitesi Adresli: Hayır

Özet

We determined activities of adenosine deaminase (ADA), 5′ nucleotidase (5NT), xanthine oxidase (XO), superoxide dismutase (CuZn SOD), and catalase (CAT) enzymes in 15 human laryngeal tissues with-differentiated squamous cell carcinomas, in 15 corresponding tumor-free adjacent tissues and in 7 normal laryngeal tissues. We found lower ADA and 5NT and higher XO, CuZn SOD, and CAT activities in cancerous tissues than those in corresponding noncancerous ones. In the correlation analysis, we established one positive intercorrelation, which was between ADA activities of tumor tissues and noncancerous adjacent tissues. We also found some significant intracorrelations between enzyme activities of the tissues, all of which were positive in cancerous ones. © 1993.