Effects of Acute L-Carnitine Supplementation on Lipid Peroxidation and Nitric Oxide Level

GÜZEL N. A. , Coskun Ş. , Eroglu H., Yilmazoglu K., ŞENEL Ö.

ASIAN JOURNAL OF CHEMISTRY, vol.21, no.3, pp.2027-2031, 2009 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 3
  • Publication Date: 2009
  • Page Numbers: pp.2027-2031


The purpose of this study was to determine the effects of acute L-carnitine supplementation on blood malondialdehyde (MDA) level as a marker of lipid peroxidation and nitric oxide (NO) level. With this aim, 8 male and 8 female total 16 national badminton players participated into this study voluntarily. Astrand protocol was used to determine the maximal oxygen consumption. Each subject received an acute dose (2 g L-carnitine before 1 h of exercise) and placebo in a randomized, double-blind crossover design, Dietary intake and exercise were replicated for 4 d prior to each trial. Blood samples were drawn by venipuncture before and immediately after exercise. No significant differences were found between measurements of with and without L-carnitine supplementation of participants as regards to all measured parameters. The result of this study shows that acute L-carnitine supplementation before I h of the exhaustive exercise does not affect lipid peroxidation and nitric oxide levels.