Effects of melatonin in reducing the toxic enects of doxorubicin


Oz E., Ilhan M. N.

MOLECULAR AND CELLULAR BIOCHEMISTRY, cilt.286, ss.11-15, 2006 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 286
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1007/s11010-005-9003-8
  • Dergi Adı: MOLECULAR AND CELLULAR BIOCHEMISTRY
  • Sayfa Sayıları: ss.11-15

Özet

Anthracycline antibiotics, such as doxorubicin and daunorubicin, constitute a group of wide spectrum therapeutic agents. Application of these drugs in chemotherapy is limited because of their toxic effects. Melatonin, the main secretory product of pineal gland, was recently found as a free radical scavenger and antioxidant.