Proposal for the standardisation of multi-centre trials in nuclear medicine imaging: prerequisites for a European I-123-FP-CIT SPECT database

Dickson J. C., Tossici-Bolt L., Sera T., de Nijs R., Booij J., Bagnara M. C., ...Daha Fazla

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, cilt.39, sa.1, ss.188-197, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 39 Sayı: 1
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1007/s00259-011-1884-z
  • Dergi Adı: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.188-197
  • Anahtar Kelimeler: Multi-centre trials, SPECT, I-123-FP-CIT, Normal database, Dopamine transporter, CLINICAL-TRIALS, PET SCANNERS, QUANTIFICATION, QUALIFICATION, RESOLUTION, NETWORK, PHANTOM, IMPACT
  • Gazi Üniversitesi Adresli: Evet

Özet

Purpose Multi-centre trials are an important part of proving the efficacy of procedures, drugs and interventions. Imaging components in such trials are becoming increasingly common; however, without sufficient control measures the usefulness of these data can be compromised. This paper describes a framework for performing high-quality multi-centre trials with single photon emission computed tomography (SPECT), using a pan-European initiative to acquire a normal control dopamine transporter brain scan database as an example.