Proposal for the standardisation of multi-centre trials in nuclear medicine imaging: prerequisites for a European I-123-FP-CIT SPECT database

Dickson, John; Tossici-Bolt, Livia; Sera, Terez; de Nijs, Robin; Booij, Jan; Bagnara, Maria; Seese, Anita; Koulibaly, Pierre; AKDEMİR, ÜMİT; Jonsson, Cathrine; Koole, Michel; Raith, Maria; Lonsdale, Markus; George, Jean; Zito, Felicia; Tatsch, Klaus

doi:10.1007/s00259-011-1884-z

Proposal for the standardisation of multi-centre trials in nuclear medicine imaging: prerequisites for a European I-123-FP-CIT SPECT database

Dickson J. C., Tossici-Bolt L., Sera T., de Nijs R., Booij J., Bagnara M. C., ...Daha Fazla

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, cilt.39, sa.1, ss.188-197, 2012 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 39 Sayı: 1
Basım Tarihi: 2012
Doi Numarası: 10.1007/s00259-011-1884-z
Dergi Adı: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.188-197
Anahtar Kelimeler: Multi-centre trials, SPECT, I-123-FP-CIT, Normal database, Dopamine transporter, CLINICAL-TRIALS, PET SCANNERS, QUANTIFICATION, QUALIFICATION, RESOLUTION, NETWORK, PHANTOM, IMPACT
Gazi Üniversitesi Adresli: Evet

Özet

Purpose Multi-centre trials are an important part of proving the efficacy of procedures, drugs and interventions. Imaging components in such trials are becoming increasingly common; however, without sufficient control measures the usefulness of these data can be compromised. This paper describes a framework for performing high-quality multi-centre trials with single photon emission computed tomography (SPECT), using a pan-European initiative to acquire a normal control dopamine transporter brain scan database as an example.