Relation of Kynurenine/Tryptophan with Immune and Inflammatory Markers in Coronary Artery Disease

Özkan Y., Şüküroğlu M. K., Tulmac M., Kısa Ü., Simsek B.

CLINICAL LABORATORY, vol.60, no.3, pp.391-396, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 60 Issue: 3
  • Publication Date: 2014
  • Doi Number: 10.7754/clin.lab.2013.121204
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.391-396
  • Gazi University Affiliated: Yes


Background: Inflammation and immune activation have a crucial role in the pathogenesis of cardiovascular diseases. Indolamine 2,3-dioxygenase, a tryptophan catabolising enzyme, is up-regulated with various inflammatory stimuli. The aim of this study was to evaluate the relationship of tryptophan degradation with immune and inflammatory markers in coronary artery disease.