PSYCHIATRIC ANNALS, cilt.52, sa.5, ss.213-218, 2022 (SSCI)
Peripheral edema is characterized by interstitial fluid accumulation in the extravascular compartment. Use of psychotropic drugs can cause edema either directly or by causing systemic disease. We present a case of bilateral ankle edema reaching up to the middle of both legs in a 50-year-old female patient, which is considered to be a result of the use of mianserin 10 mg/day. Dramatic regression was observed in the patient???s edema 15 days after the cessation of mianserin. This is the second case in the literature that demonstrated peripheral edema associated with mianserin. Clinicians need to know about the management of edema and edema associated with the use of antidepressants.