ChatGPT-4o vs Psychiatrists in Responding to Common Antidepressant Concerns
American Journal of Health Promotion, cilt.40, sa.1, ss.10-17, 2026 (SSCI, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 40 Sayı: 1
- Basım Tarihi: 2026
- Doi Numarası: 10.1177/08901171251348208
- Dergi Adı: American Journal of Health Promotion
- Derginin Tarandığı İndeksler: Social Sciences Citation Index (SSCI), Scopus, Academic Search Premier, ASSIA, Abstracts in Social Gerontology, CAB Abstracts, CINAHL, EBSCO Education Source, EMBASE, Food Science & Technology Abstracts, MEDLINE, PAIS International, Psycinfo, Public Affairs Index, SportDiscus, Veterinary Science Database
- Sayfa Sayıları: ss.10-17
- Anahtar Kelimeler: accuracy, antidepressants, artificial intelligence in healthcare, ChatGPT, psychiatrists
- Gazi Üniversitesi Adresli: Evet
Özet
Purpose: Artificial intelligence (AI) is increasingly integrated into healthcare, including psychiatric care. This study evaluates ChatGPT-4o’s reliability in answering frequently asked antidepressant-related questions by comparing its performance with psychiatrists across four key dimensions: accuracy, conciseness, readability, and clarity. Design: A comparative study analyzing ChatGPT-4o-generated responses and those of psychiatrists with at least five years of clinical experience. Setting: Participants were recruited through institutional and professional networks and provided with standardized questions derived from authoritative treatment guidelines. Subjects: Twenty-six psychiatrists participated, and ChatGPT-4o responses were generated using a standardized prompt for each question. Measures: Two independent psychiatrists evaluated accuracy and conciseness using a blinded rating system. Readability was assessed with the Flesch-Kincaid Grade Level test, and clarity was measured with the Writing Clarity Index Calculator. Analysis: The Shapiro-Wilk test assessed normality. Paired t-tests were used for normally distributed data, and the Wilcoxon signed-rank test for non-normally distributed data. Statistical significance was set at P <.05. Results: ChatGPT-4o showed comparable accuracy to psychiatrists (P =.0645) but was significantly more concise (P =.0019). Readability differences were not statistically significant (P =.0892), while psychiatrists provided clearer responses (P =.0059). Conclusion: ChatGPT-4o delivers accurate and concise responses, highlighting its potential as a patient education tool. However, psychiatrists offer greater clarity, underscoring the indispensable role of clinical expertise in psychiatric care.